USPS Priority Express Mail is the fastest domestic service offered by the United States Postal Service. This service guarantees overnight delivery to most locations, with delivery by 10:30 AM or noon the next day, depending on the destination. Priority Express Mail is perfect for urgent shipments that need to arrive quickly. It offers a variety of features, including tracking, insurance, and signature confirmation. This service is available 7 days a week, including holidays, which makes it one of the most reliable options for time-sensitive deliveries. Although it comes at a higher cost than standard Priority Mail, the guarantee of next-day delivery makes it invaluable for businesses and individuals who need their items delivered as quickly as possible.